Integrated Report 2024

PHC Group Business StrategyDiagnostics & Life Sciences

Contributing to improved patient outcomes through
groundbreaking technology to support cancer diagnostics.

Steven Lynum

Steven Lynum

Corporate Officer, PHC Holdings Corporation
President, Epredia Holdings Ltd.

Message

Epredia's name comes from our mission: to improve lives by “enhancing precision cancer diagnostics.” We provide solutions for anatomical pathology testing related to cancer diagnostics. We have a strategic vision to be the best provider of end-to-end precision diagnostics solutions, and our work seeks to ultimately reduce the burden of disease and the environmental impact of medical care by improving the pathology laboratory workflow. We are committed to serving our customers, and ultimately the patients they serve, with the highest quality products and services in laboratories around the world.

Main Customers

  • Hospitals/clinics
  • Research institutions/universities
  • Pharmaceutical companies

Overview

Epredia is a global leader in the field of anatomical pathology, providing comprehensive solutions for precision cancer diagnostics with the goal of contributing to better outcomes for patients.
Anatomical pathology involves observing organs and tissues and diagnosing whether tissues are benign or malignant, and is essential for cancer diagnostics and treatment. A collected tissue specimen goes through many processing steps in a pathology lab before being placed on a glass slide for observation and diagnosis, and Epredia offers a wide range of products to make the laboratory workflow more efficient and effective. Known for product brands such as Shandon, Richard-Allan Scientific, Microm, and Menzel Glaser, the company has been providing solutions for precision cancer diagnostics since its founding in 1937.
Currently, 48 Epredia products are used every second in medical institutions and research facilities around the world. We will continue to drive innovation to help improve the lives of cancer patients worldwide.

Strengths

  • Comprehensive, state-of-the-art technology for laboratories
    Epredia provides high-quality instrumentation and consumables necessary for pathology laboratories working with tissue samples. Key products include glass microscope slides that are recognized for their excellent adhesion quality and exceptional clarity. Each piece of equipment is designed with pathologists’ needs in mind such as ergonomics and ease of use, with the goal of contributing to efficient and accurate cancer diagnosis for the patient.
  • Innovative products powered by digital technology
    Typically, specimens prepared on glass slides are observed by pathologists using a microscope, but in recent years digital pathology technology has emerged in which tissue specimens can be scanned as digital images and viewed on a computer screen. Technology may soon be developed to use AI image recognition to analyze these digital images to support cancer diagnostics. Epredia is offering AI solutions to our customers through our partnership with companies Paige and Aiforia.
  • Strong customer base and high market share
    Epredia has trusted relationships with customers and a high market share that has been cultivated over the last 85 years. In particular, we are often viewed as the worldwide leader for microscope slides and tissue processors.

What’s new

Epredia is a global leader in precision cancer diagnostics solutions. With a foundation built on high-quality and reliable instruments, reagents, and microscope slides, we strive to deliver new value in the clinical and research fields through digital imaging using digital scanners and supporting AI-driven diagnostics.
In FY2023, we introduced the award-winning SlideMate Laser printer, designed to improve tissue sample tracking and efficiency by enabling laboratories to embed more detailed information directly on the slides used in the cancer diagnostics workflow. Additionally, we launched the E1000 Dx Digital Pathology Solution designed to maximize laboratory productivity for diagnostic use in the United Kingdom.
On the manufacturing front, we commenced the production of equipment made specifically for the Chinese market at our 100,000 square-foot Shanghai facility. We are now working to optimize the efficiency of our production systems globally by deploying engineers from other PHC Group companies to share and implement best practices from our rich legacy in Japanese manufacturing.
As a frontrunner in anatomical pathology products designed to improve the laboratory workflow, we remain committed to providing cutting-edge value that enhances precision diagnostics. (As of March 2024)

Employee Voices

For the past twenty years, the Epredia Portsmouth team has been delivering innovative, quality OEM microscope slides used specifically for cervical cancer screening. This type of product must be free of any fungal contamination, which could result in a misdiagnosis or even worse, unnecessary treatment. Our team takes great pride in meticulously processing the slides to meet this critical healthcare need. The packing department, which is currently comprised of all women, can personally relate to how important this slide is as part of an annual gynecological visit. With that in mind, they have a deep
understanding and appreciation of the quality criteria we must meet every day.

Lisa Julian

Deputy Site LeaderLisa Julian

Main Products/Services

  • Slide Glass
    High-quality pathological diagnosis requires high-quality microscope slides. Our unique glass manufacturing technology enables smooth surfaces and uniform thickness, supporting high-quality specimen analysis and highly accurate diagnosis.
  • Pathology Reagents
    Cytology staining, which provides clear contrast between cytoplasm and nuclear chromatin, is an important component in cancer diagnostics. Epredia’s staining equipment is designed to stain tissue samples with high transparency and sharpness, and can be used in combination with a variety of staining solutions.
  • Pathology Equipment
    Tissue processing is critical to obtaining reliable results in the histology laboratory. Laboratories are under pressure to speed up processes, reduce costs, and prevent operational errors. Epredia’s tissue processing solutions are designed to efficiently produce high-quality paraffin blocks to enable pathologists to make an accurate diagnosis.
  • Labeling and Management Solutions
    To prevent operational errors in the histology laboratory, cassettes and microscope slides must be labeled, properly recorded, and tracked. Epredia’s cassette printers and slide printers with laser technology and on-demand printing capabilities provide an automated way of labeling and tracking laboratory samples and slides, to increase accuracy while streamlining workflow.
  • Slide Glass

    Achieve more accurate diagnosis with the highest level of optical clarity.

    Slide Glass
  • Pathology Reagents

    Streamline microscopic observation of cytoplasm and chromatin with a highly transparent and cost-effective staining solution.

    Pathology Reagents
  • Pathology Equipment

    Streamline the work of applying reagents to samples and reduce reagent costs.

    Pathology Equipment
  • Labeling Solutions

    Automate printing of slides and cassettes to streamline workflow.

    Labeling Solutions
  • Digital Pathology

    Contributing to the future of digital pathology solutions through partnership with 3DHISTECH.

    Digital Pathology

* In-house research

Epredia(Pathology Division)

Epredia(Pathology Division)

The number of cancer diagnoses is increasing worldwide, and as a result, cancer-related drug development activities are expanding, especially among pharmaceutical companies. In this environment, the market for pathology testing equipment and consumables is expected to grow at a mid-single-digit rate.
We are focusing on the areas of digital pathology and immunohistochemical staining. Digital pathology supports cancer diagnostics using digital images rather than a microscope. Additionally, when it is necessary to confirm what kinds of proteins are distributed in cells and tissues, a technique called immunohistochemical staining is used. These technologies are attracting attention for their potential to greatly improve the efficiency of cancer diagnostics and pharmaceutical research and development, and are expected to grow by double digits annually.
Pathology is an area where high quality and stability are especially critical, and we will continue to develop new high-quality products and seek to increase our market share.
Additionally, in the growing field of digital pathology, we offer digital pathology products including those made by our partner 3DHISTECH. As a partner in immunohistochemical staining with 3DHISTECH, we jointly operate a research and development laboratory, the Pathology Innovation Incubator (Pi2), and we will invest heavily in the growth of digital pathology and immunohistochemical staining.

The E1000 Dx Digital Pathology Solution, developed from a practitioner's perspective and based on the experience and knowledge of physicians, is now available in the UK. The scanner can load up to 1,000 slides at once and automatically scan them in about half a day.
Scanning during the night and sharing the data among pathologists the next day, for example, enables high volume and rapid observation irrespective of the pathologist's location. This contributes to making the diagnostics process more efficient.

E1000 Dx&trade