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Cell3Imager NX

SHC-CC-100

Cell3iMager NX - Imager for cells cultured in 2D/3D
Equipped with high-definition stitching function

Features

Cell3iMager NX IMAGER FOR CELLS CULTURED IN 2D/3D

High-throughput Imager for analysis cells cultured in 2D and 3D environment. Cell3iMager NX offers high-speed, high-quality image acquiring and quantitative data analysis with all-in-one software package.

High-definition Stitching Technology

The well is divided into multiple s ots during the scan. The split images are t en stitched together using SCREEN's proprietary high-definition stitching technology to minimize the number of image gaps (see image below) and to clearly image the entire well for accurate analysis.

Focus Composition Technology

Automatic stacked imaging of objects scattered in the Z-axis direction while changing the focus position. SCREEN's proprietary image processing technology is used to construct all-in-focus images.

Options

Deep learning

In the case of high-confluency and non-uniform images, it is difficult to segment by luminance shading and edge thresholding. For example, even in the case of overlapping images such as the one shown below, segmentation may be possible using Deep Learning.

Deep Learning Applications

Deep learning can be used for highly accurate segmentation of the following challenging image examples.

Multi-color Fluorescence

Supports multi-color fluorescence imaging. Up to five fluorescent filters can be mounted simultaneously, enabling automatic bright-field/fluorescent four-color imaging.

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Applications

  • Cell Morphology
  • Cell Proliferation
  • Cell Viability Growth Inhibition
  • Cell/Colony Count
  • Multiplex assays: LIVE/DEAD Cytotoxicity
  • Single Cell Detection
  • Routine Quality Monitoring
  • Cell Adhesion/Extension
  • Single Cell Cloning
  • Cell Migration (Scratch Assay)
  • 3D Organoid/Spheroid Morphology
  • Drug Screening 2D & 3D Cell Based
  • Drug Efficacy
  • Drug Activity and Profiling (2D & 3D Spheroid)
  • Growth Rate Monitoring (2D & 3D Spheroid Assays)
  • Colony Formation Assay
  • iPS Cell Line Generation
  • iPS Cell Characterization
  • iPS Cell Differentiation
  • Hybridoma Cell culture
  • Stem Cell Marker Analysis
  • Cell Body/Neurite Analysis
  • Evaluation of Anti-Angiogenics
  • Apoptosis Assays
  • Hepatotoxicity Assay
  • Embryoid Body Morphology
  • Foci & Plaque Counting
  • Fluorescence Titer Quantification
  • Transfection/Transduction Efficiency
  • CRISPR Fluorescent Reporter Monitoring
  • Nuclear Translocation
  • Reporter Gene Assay
  • Immuno-Cyto Chemistry
  • DNA Synthesis
  • Biomarker Quantification
  • Cell Cycle & Mitosis

Product Photos

Specifications

Dimensions (WxDxH) 500 × 500 × 530 mm
Weight [Kg] 44
Lighting Unit LED transparent lighting (white) / Switching aperture (2types) /Automatic phase difference shutter
Camera CMOS 12Mpixel monochrome
Auto Focus Light source Laser diode / Detection range -0.5mm~3.5mm
Magnification 4x, 10x objective lens (standard) 2x, 20x, 40x, 10x phase difference, 20x phase difference (options)
Supported Plates 6,12,24,48,96,384 well plate etc. 35,60,100 mm dish, glass slide
Image Output 8bit mono
Scanning resolution 20320dpi (4x) / 50800dpi (10x)
Fluorescent Filters 5 colors
Channel Bright Field and 4 Colors of Fluorescence
Power Supply AC100-240V / 190VA
Internal temperature Adjustable between 18°C ± 2°C and 40°C ± 2°C in 1°C increments (without cooling mechanism)
Environment 18-28°C, humidity less than 80%, no condensation
Automation Support Available
Software Cell3imager NX dedicated software (Standard)
  • Imaging, Analysis and Export
  • Neurite projection measurement
  • Data security functions (database management/user management/audit trail) Time-lapse function (Options)
    Deep Learning Plug-ins
    Robot interface

    Controller

    External dimensions (WxDxH) 371 mm x 197 mm x 220 mm
    Screen 12.1-inch-wide touch panel display
    Extendability Wired connectivity for up to 4 detectors
    Items monitored Glucose, lactate (simultaneous continuous
    measurement of both items)
    Monitoring duration Maximum 10 days
    Measurement range Glucose: up to 27 mM (up to 4.9 g/L)
    Lactate: up to 15 mM (up to 1.4 g/L)

    Dimensions

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