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Cell Expansion System

LiCellGrow

Features

Real-time Wave-mixing Bioreactor

Licellgrow - Cell-expansion-system

 

Continuous measurement by the in-line sensors allows visualization of glucose and lactate concentration evolution

Glycolysis is one of the major energy metabolism pathways in cells. Since in this process glucose is consumed and lactate is produced, changes of their concentrations are a useful index for cell vitality. The Culture Bag is equipped with an in-line sensor, which measures glucose and lactate in real time as continuous in-line data.

Culture medium is replaced automatically based on real-time measurement and analysis

The Real-time Wave-mixing Bioreactor measures the concentrations of glucose and lactate in real-time and automatically replaces the culture medium based on the measured values. An optimal and stable supply of glucose is guaranteed and exposure to elevated levels of lactate is avoided.


 

Closed system cell culture with single-use Culture Bags

The dedicated Culture Bags are gas-permeable, single-use bags, each fitted with an In-Line Sensor. This system eliminates the need for sampling, greatly reducing the risk of contamination.

Highly reproducible cell culture with guaranteed sterility

The Culture Bags with in-line sensors are gamma-irradiated before supply and simply need to be fitted to the device to ensure a sterile environment for highly reproducible cell cultures.

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Product Photos

Specfications

Product Overview

Monitoring parameters Glucose, lactate (simultaneous measurement of both parameters) pH/DO (simultaneous measurement of both parameters) *pH/DO measurement is available as an option
Main Device Components Processor, controller
Main consumables (single use) Culture Bag, Sensor Helder, Reservoir Bag, Waste Bag
Culture Bags Capacity
  • 600 ml (minimum culture volume 100 ml)
  • 1200 ml (minimum culture volume 300 ml)
  • Main Device Components Processor, controller
    Monitoring time Maximum 10 days
    Measurement ranges Glucose: 1-27 mM or less
    Lactate: 1.5-15 mM or less
    pH: 6.0-8.0
    DO: 0-250% a.s. (a.s.= air saturation)s

    Processor

    Dimensions Width 410 mm x Depth 410 mm x Height 400 mm
    Installation Inside C02 incubator

    Controller

    Dimensions Width 371 mm x Depth 200 mm x Height 295 mm
    Screen 15.6-inch wide touch-panel display

    Dimensions

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